hrp0097p1-337 | Multisystem Endocrine Disorders | ESPE2023

Occurrence of central hypothyroidism in children with isolated growth hormone deficiency

Mayer Judith , Schweizer Roland , Binder Gerhard

Background: A small subgroup of children with isolated growth hormone deficiency (IGHD) develop central hypothyroidism (CH) during GH treatment. Prognostic parameters are still unclear.Objective and hypothesis: Long-term evaluation of children with initial diagnosis of IGHD to identify those with an unmasking CH under GH treatment. IGHD was diagnosed in children with short stature, low height velocity, retarded bone age,...